dopamine modulation by stimulant self - administration

1. Abstract 2. Introduction 3. Nucleus accumbens 4. Stimulant actions 4.1. Cocaine and amphetamine 4.2. In vitro brain slice voltammetry 4.3. Microdialysis 4.4. Differences in dopamine signaling within the nucleus accumbens 4.5. Time of onset of cocaine and other dopamine transporter inhibitors 5. Neurochemical consequences of cocaine and amphetamine self-administration 5.1. Reduced responsivity to cocaine following cocaine self-administration 5.2. No changes following amphetamine self-administration 6. Potential mechanisms for altered dopamine signaling following cocaine self-administration 7. Conclusions 8. Acknowledgement 9. References